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Predisposition: People who have a history of obesity or other metabolic disorders may be at a risk of gaining weight when taking any medication, including Gabapentin
Thank you!" - Amy S
One other downside that I think you didn't point to specifically, but you meant in saying there's some unknown downside to this, there are some early studies that are showing that you lose more lean muscle mass when you're on a GLP-1 than if you were just doing diet and exercise

In 87% ( n = 277) of randomized participants, liver biopsy at week 72 was available to evaluate the primary endpoint of resolution of MASH and the confirmatory secondary endpoint of improvement of at least one fibrosis stage and no worsening of MASH
