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The two primary incretin hormones are: GLP-1 (glucagon-like peptide-1) GIP (glucose-dependent insulinotropic polypeptide) These hormones support metabolic balance by stimulating insulin secretion, inhibiting glucagon release (which would otherwise raise blood sugar), slowing gastric emptying (to help regulate the pace of digestion), and promoting a feeling of fullness or satiety, which can reduce overall food intake

Get a comprehensive hormone panel If you have not had your sex hormones checked since starting GLP-1 therapy, request a full panel including total and free testosterone, estradiol, SHBG, LH, FSH, and thyroid function

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Participants in tirzepatide groups had statistically significant mean reductions in HbA1c from baseline compared with those in the dulaglutide group, which began at week 4, were near the maximum around week 24, and were maintained until week 52