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Runny nose and nasal congestion are not listed as common side effects in clinical trials of semaglutide, yet some patients report these symptoms during GLP-1 treatment

Secondary outcomes included absolute change in body weight and weight circumference from 36 to 88 weeks, the percentage of adults achieving at least a 5%, 10%, 15%, 20% or 25% weight loss from baseline to 88 weeks and the percentage of adults that maintained at least 80% of the body weight they lost during the open-label period

Evidence is still lacking concerning whether microglial activation precedes the emergence of GCIs

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