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Overall, these results are in line with enhanced GLP-2R action, previously shown to increase villus length by promoting intestinal cell proliferation and inhibiting apoptosis at the villus tip 17

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The paper by Hathaway and colleagues has now opened a second area of interest, more specifically related to semaglutide and a potentially increased risk of NAION. GLP-1 agonists have become popular in recent times, and based on the sheer volume of patients who are on them, an increasing number of these reactions are to be expected

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