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Overall, these results are in line with enhanced GLP-2R action, previously shown to increase villus length by promoting intestinal cell proliferation and inhibiting apoptosis at the villus tip 17

The paper by Hathaway and colleagues has now opened a second area of interest, more specifically related to semaglutide and a potentially increased risk of NAION. GLP-1 agonists have become popular in recent times, and based on the sheer volume of patients who are on them, an increasing number of these reactions are to be expected

Anyone in those situations should not be considering retatrutide outside qualified medical care

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