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This effectiveness gap is crucial when weighing Mounjaro vs Trulicity for blood sugar management
This study was carried out in accordance with relevant guidelines and regulations including the Declaration of Helsinki

In the Phase 3 ATTAIN-1 trial published in the New England Journal of Medicine in 2025, once-daily orforglipron produced mean body weight reductions of 7.5% (6 mg), 8.4% (12 mg), and 11.2% (36 mg) at 72 weeks, compared with 2.1% for placebo

Prog Lipid Res 2009;48:1-26
