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Rationale and protocol of the Dapagliflozin And Prevention of Adverse outcomes in Chronic Kidney Disease (DAPA-CKD) randomized controlled trial

Despite inherent limitations of observational data and potential for residual confounding, the results from these observational analyses support, in line with RCT findings, combining SGLT2is and GLP-1RAs to reduce cardiovascular events in patients with diabetes in routine clinical care [12, 23, 43, 63]

The Best Strategy for Strong Results: GLP-1s Plus Lifestyle Changes A study presented at the AUA 2024 meeting 4 and published in the Journal of Urology explored the effects of GLP-1 receptor agonists on male reproductive health and impact of diet and lifestyle
