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Medication selection also depends on health history, side-effect tolerance, diabetes status, pregnancy plans, medication interactions, insurance, cost, availability, and individual treatment goals

Sources Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial (2024) Journal of the American Medical Association [Accessed 2 December 2025] Dosing Schedule | Ozempic (semaglutide) (2025) [Accessed 2 December 2025] GIP and GLP1, the two incretin hormones: Similarities and differences (2010) Journal of Diabetes Investigation [Accessed 2 December 2025] Once-Weekly Semaglutide in Adults with Overweight or Obesity (2021) New England Journal of Medicine [Accessed 2 December 2025]