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General guidance: Theres no need to wash out one medication before starting the other You can typically switch directly from one medication to the other Your prescriber will advise on the appropriate starting dose based on your current dose Some weight fluctuation during the transition is normal Read our full guide on how to switch providers here

24.2% weight loss at 48 weeks Massive metabolic improvements More research needed on long-term safety Other GLP-1/Glucagon Drugs Survodutide, Pemvidutide, and Cotadutide are in earlier or mid-stage development, with Survodutide showing the strongest results so far

Ongoing or severe pain should not be managed at home, as gallbladder complications may require investigation or treatment

First approved in 2017 for treating Type 2 diabetes, Semaglutide effectively stabilizes glycemic levels by boosting insulin secretion and reducing glucagon secretion, ultimately stabilizing blood sugar