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260263 Increased intestinal GLP-1 secretion after gastric bypass surgery appears to be sustained and can potentially have beneficial effects in terms of weight loss and long-term remission of T2DM

This modification, along with albumin binding facilitated by a fatty acid side chain, extends the half-life to approximately one week, allowing for once-weekly subcutaneous administration

Smoking cessation is strongly advised, as tobacco use impairs lower oesophageal sphincter function and reduces saliva production (which naturally neutralises acid)

[DOI] [PubMed] [Google Scholar] 50.Guardado Mendoza R, Perego C, Finzi G, et al