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Why Your Dose Increases and What to Expect Your dose increases because initial lower doses are safety introductionsthey let your body acclimate to the medication's effects on appetite and digestion

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doi: 10.1098/rstb.2006.1860 12 HirschbergAL

Most people notice subtle appetite changes within the first one to two weeks of starting semaglutide at 0.25 mg
