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2020 global estimate and projected number of adults through 2035 with an overweight BMI [1]. Obesity is a significant independent risk factor contributing to numerous chronic conditions, including diabetes, hypertension, cardiovascular disease, and obstructive sleep apnea syndrome

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For a while, one of the big worries in obesity pharmacotherapy has been pretty simple: when body weight drops fast, how much of that is fat, and how much is the tissue you really want to keep
