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dissected GLP-1R-expressing lumbar dorsal root ganglion neurons from mice and cultured them with Schwann cell-conditioned media to mimic diabetic conditions ( in vivo experiments, the authors treated the streptozotocin-induced DM mice with exendin-4 at 10 nmol/kg for 4 weeks and found that exendin-4 promoted the peripheral nerve function as reflected by improved current perception threshold and motor and sensory nerve conduction velocity

Tiredness and limb heaviness usually improve

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A calibrated, low-dose dual agonist formulation designed to help support appetite regulation and healthy metabolic function