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Understanding how GLP-1 regulates inflammation (Figure 1) provides insights into the pleiotropic weight lossindependent benefits of GLP-1R agonism, potentially explaining its actions to reduce the severity of several chronic diseases marked by dysregulated immune function and inflammation

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This experience, often described as a reduction in food noise with GLP-1 therapy, reflects measurable neuroendocrine shifts in appetite regulation and reward signaling