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To further elucidate which GLP-1R-expressing cells are involved in the abovementioned cardio- and vasoprotective benefits, liraglutide was administered to wild-type (C57BL/6J), global Glp1r knockout ( Glp1r / ), endothelial cell- ( Cdh5 Cre ) and myeloid cell ( LysM Cre )-specific knockout of Glp1r and arterial hypertension was induced by angiotensin II

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