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Shen S., Liu B., Fanti C., et al., GlucagonLike Peptide1 (GLP1) Agonist Use and Weight Change Among Patients With Breast Cancer, Journal of Clinical Oncology 42 (2024): 10607
This mechanism helps control post-meal blood sugar spikes while creating a sustained feeling of satiety that naturally reduces caloric intake
So far, no significant hypoglycaemia signal has been seen, likely because GLP-1 and GIP agonism counterbalance glucagons glucose-raising effect, but this remains an area of ongoing surveillance
Glucagon-like peptide-1 and insulin synergistically activate vagal afferent neurons
