soul trial oral semaglutide cardiovascular outcomes 2024 2025 Reduces CV Events in T2DM β (NEJM, Mar 2025) Relevant for: cardiology, diabetology, nephrology, internal medicine π§ͺ T2DM + ASCVD/CKD π Oral semaglutide 14 mg vs placebo π Cardiovascular Outcomes Associated with Semaglutide
Description
Semaglutide, the active ingredient in well known injectables like Ozempic and Wegovy, works by mimicking GLP-1, a hormone that helps regulate blood sugar, curb cravings, and promote steady weight loss.

and Novo Nordisk A/S were sued Wednesday by a top compounding pharmacy that makes copycat versions of their blockbuster obesity and diabetes drugs.

This study demonstrates that semaglutide alleviates PCOS phenotypes and reverses ovarian granulosa cell ferroptosis
Ten units of semaglutide can produce weight loss in some patients, but individual response varies based on genetics, metabolism, and starting body composition
