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The STEP 1 extension study showed that participants who stopped semaglutide regained approximately two-thirds of their lost weight within one year

Surg Obes Relat Dis (2016) 12(3):7024.10.1016/j.soard.2015.08.503 78 SpiegelKTasaliELeproultRScherbergNVan CauterE

A slower-absorbing formulation might produce a gentler curve