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Description
The double mutation of N302 ECL2 -M303 ECL2 to Val-Lys caused a small affinity reduction with a 10-fold decrease in potency (Moon et al., 2012)

Ventre G, Colonna C, Smith J, Alfano D, Moldow R

As a result, after childbirth, many women consider losing weight, and there seems to be a growing interest in the use of semaglutide for this purpose

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