retatrutide glp-1 gip glucagon agonist Structural insights into the triple agonism at GLP-1R, GIPR and GCGR manifested by Retatrutide Api Triple Gip Glp-1
Description
Work in the area has been confounded by concerns that GLP-1 pills could cause harsh side effects and discourage patients from taking them

Fernando, K
If the efficacy readouts from SURMOUNT-1 are reproducible, Lilly almost certainly has a best-in-class medication this may be plainly reflected in the SURMOUNT-5 Phase 3b trial readout (1H 2025)

In other GLP-1 medications like Ozempic, Trulicity, or Victoza, fatigue is less frequently reported or not specifically listed as a common side effect in FDA prescribing information
