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Both are weekly injectable GLP-1 medications but tirzepatide works on two hormone receptor systems (GLP-1 and GIP) instead of one

However, if you plan to stop the medication, its crucial to work with your healthcare provider to develop a plan to maintain your weight loss through lifestyle changes.

Without an FDA-approved retatrutide product, there is no legal source ingredient for compounding, and any pharmacy or individual offering compounded retatrutide is operating outside FDA regulations

Many people who feel tirzepatide is not working anymore are actually dealing with timing inconsistencies rather than true tolerance