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glp-1 receptor agonists and cancer risk in adults with obesity show anti-cancer benefits beyond weight loss The effect of GLP-1R agonists

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Glucagon-like peptide I and glucose-dependent insulinotropic polypeptide stimulate Ca2+-induced secretion in rat alpha-cells by a protein kinase A-mediated mechanism

glp-1 receptor agonists and cancer risk in adults with obesity show anti-cancer benefits beyond weight loss The effect of GLP-1R agonists

Exendin-4 degrades more slowly than the human form of GLP-1, lasting for hours instead of minutes

glp-1 receptor agonists and cancer risk in adults with obesity show anti-cancer benefits beyond weight loss The effect of GLP-1R agonists

The STEP-HFpEF trial randomised 529 patients with obesity (BMI 30 kg/m 2 ), HFpEF (left ventricular ejection fraction [LVEF] 45%) and New York Heart Association (NYHA) Class II symptoms to once-weekly subcutaneous semaglutide 2.4 mg or placebo

glp-1 receptor agonists and cancer risk in adults with obesity show anti-cancer benefits beyond weight loss The effect of GLP-1R agonists

Adapted from Kadowaki et al

glp-1 receptor agonists and cancer risk in adults with obesity show anti-cancer benefits beyond weight loss The effect of GLP-1R agonists

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