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Description
Another drug class widely used to treat type 2 diabetes is inhibitors of the enzyme dipeptidyl peptidase-4 (DPP4), which mediates enzymatic breakdown of GLP-1

Some studies have reported better preservation of renal function with SGLT2i than with GLP-1RA [19,20,21], while others have reported similar kidney outcomes with either drug class [22, 23]
doi: 10.3389/FENDO.2022.1033479 23 KoppKOGlotfeltyEJLiYGreigNH
Even in this setting, noninvasive imaging studies fail to detect 20% to 25% of insulinomas so that a negative study does not exclude the diagnosis (14)
