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As of 28 October 2024, the UK Government's med watch database (MHRA) received over 7,000 reports of gastrointestinal side effects linked to GLP-1RAs, with some resulting in hospitalization

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If you are considering berberine, consult your GP or pharmacist first , particularly if you: Take prescribed medications for diabetes, cardiovascular disease, or other chronic conditions Are pregnant, planning pregnancy, or breastfeeding Have liver or kidney disease Are scheduled for surgery (berberine should be stopped at least 2 weeks before elective procedures) When to seek medical advice: Contact your GP if you experience persistent gastrointestinal symptoms, signs of hypoglycaemia (tremor, sweating, confusion, palpitations), unusual fatigue, or any concerning symptoms after starting berberine

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