can glp 1 cause diabetes GLP‑1 Drugs: Obesity & Treatment Fight GLP-1: Actions on Beta-cell Mass

GK, MBW, and PB provided access to key reagents and experimental core facilities

adults of obesity patients with or without T2DM

In a mixed-treatment comparison meta-analysis of randomized controlled trials of GLP-1 receptor agonists (exenatide BID and QW and liraglutide) in overweight or obese patients with type 2 diabetes, mean reductions in body weight were greater than with placebo for exenatide 10 g BID (1.4 kg), exenatide QW (1.6 kg), and liraglutide 1.8 mg (1.5 kg), with no significant differences among these three treatments (24)

Data availability The datasets analysed during the current study are available from the corresponding author on reasonable request