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Conflict of interest Author AA has received consulting fees from AbbVie, Allergan, Amgen, Arena, Biogen, Boehringer Ingelheim, Bristol-Myers Squibb, Celgene, Celltrion, Eli-Lilly, Ferring, Galapagos, Gilead, Janssen, MSD, Mylan, Pfizer, Protagonist Therapeutics, Roche, Samsung Bioepis, Sandoz and Takeda

The equations and criteria for these algorithms (Supplementary Table S2

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Potential safety issues Pancreatic and thyroid risk Beyond gastrointestinal adverse events, which are widely accepted as a class effect of GLP-1 RAs, 65 , 66 several other safety concerns have been raised over the past decade