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Description
Patients considering these supplements should understand that symptom relief, if experienced, may result from placebo effects or natural symptom resolution over time rather than the enzymes themselves

Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work

The study provides new insight into the potential benefits of Metformin and could lead to the development of new treatments for pain

In this study, 475 patients were randomized
