what do glp-1 drugs do receptor agonists Can one drug do it
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Earlier meta-analyses did report a small on-medication motor benefit, roughly one to three points, but that effect is heterogeneous and fragile: in at least one pooled analysis, it lost statistical significance once the lixisenatide trial was removed [8]

[DOI] [PMC free article] [PubMed] [Google Scholar] 61.He L., Wang J., Ping F., Yang N., Huang J., Li Y., Xu L., Li W., Zhang H

PMCID: PMC11034947

reported greater weight loss in obese mice with the GLP-1/GIP/glucagon receptor triagonist compared to GLP-1 receptor agonists, GIP/GLP-1 receptor co-agonists and GLP-1/glucagon receptor agonists including semaglutide and tirzepatide [60]
