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In addition, the use of valproic acid with or without other anticonvulsants may cause hepatotoxicity and increase plasma ammonia concentrations, leading to encephalopathy
Management should be individualized based on symptom severity, patient tolerance, and treatment goals
Ethics declarations Ethics approval and consent to participate The study followed the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines and received ethical approval from the Institutional Review Board of Chung Shan Medical University Hospital (IRB number: CS2-21176)
