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Despite their remarkable clinical success, several real-world barriers have constrained broader adoption

Summary This systematic review and meta-analysis aims to explore the different therapeutic effect of semaglutide on weight control under the diverse administration circumstances

Participants who presented a weight loss of 5 kg or greater by week 12 were enrolled for the second phase of the study the 72-week-long trial involving the use of either the maximum tolerated dose (MTD) of tirzepatide (10 15 mg) or a placebo

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