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Description
May provide additional metabolic benefits, including improved beta-cell function, reduced glucagon secretion, delayed gastric emptying, and increased satiety 22

The combined effect of these three receptor pathways on the GI tract means that digestive side effects including nausea, vomiting, constipation, and symptoms consistent with acid reflux are a recognised feature of this drug class
Just the usual and expected GI side effects that come with the GLP-1 RAs, such as nausea, diarrhea, and vomiting

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