semaglutide side effects heart TrimRX The Cardioprotective Effects of Semaglutide

Esler WP, Rudolph J, Claus TH, et al

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Mechanisms beyond Weight and Adiposity The study suggests that semaglutide protects the heart through several mechanisms

The effects of delayed gastric emptying may further compound the risk factors harbored by the obese, diabetic patient: Gastroparesis secondary to diabetes-related autonomic dysfunction Bowel dysmotility from opioids (chronic pain) and prolonged bed-rest Altered oesophageal-gastric anatomy from bariatric surgery Gastric insufflation from overzealous bag-valve ventilation with high PEEP and difficult airway Reduced efficacy of routine antiemetic regime Nausea and vomiting are reported by approximately 50% of patients using GLP-1 agonists, as direct results of reduced gastric motility and activation of central satiety centers