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The main limitations in their oral administration are the poor absorption through the gastrointestinal tract and the rapid degradation caused by proteolytic enzymes and the acidic environment of the stomach
doi: 10.1002/dmrr.v29.1 32 SchauerIESnell-BergeonJKBergmanBCMaahsDMKretowskiAEckelRHet al
The International Agency for Research on Cancer (IARC) published a paper in 2016 that examined 1000 epidemiologic studies on the effect of body habitus on cancer risk
