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GLP-1 medications (semaglutide/Wegovy, tirzepatide/Zepbound) have become incredibly popular for women dealing with midlife weight gain

For example, a 2025 patent from Novartis describes linking a cyclic peptide that targets a receptor implicated in cancer to a cancer-killing radionuclide or cytotoxic drug

Opposite regulation of ghrelin and glucagon-like peptide-1 by metabolite G-protein-coupled receptors
