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Even patients who had already used another GLP-1 medication saw better results with tirzepatide
On Monday, Novo Nordisk announced that two large studies failed to find any effect of the drug semaglutide on cognition and functioning in people with mild cognitive impairment an early stage of Alzheimers or with dementia

Nicklas BJ, You T, Pahor M (2005) Behavioural treatments for chronic systemic inflammation: effects of dietary weight loss and exercise training

Both processes depend on stable dopamine signaling and healthy function in the anterior cingulate cortex and dorsolateral prefrontal cortex