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doi: 10.1016/S0140-6736(21)01443-4 [DOI] [PubMed] [Google Scholar] 27.Del Prato S., et al., Tirzepatide versus insulin glargine in type 2 diabetes and increased cardiovascular risk (SURPASS-4): a randomised, open-label, parallel-group, multicentre, phase 3 trial
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By replicating GLP-1s natural activity, Ozempic reduces appetite, increases satiety (the feeling of fullness), and helps control food intake

Common side effects include nausea, vomiting, and gastrointestinal upset from tirzepatide, plus appetite suppression that may complicate prednisone's appetite-stimulating effects
