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The linker (Gly 4 Ser) 3 Ala was carefully selected to retain high GLP-1R affinity as direct fusion dramatically reduced in vitro activity by 95%

The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity

Feinstein, T
[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Bisanz J.E., Enos M.K., PrayGod G., Seney S., Macklaim J.M., Chilton S., Willner D., Knight R., Fusch C., Fusch G., et al
