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The published research record is extensive for an unapproved compound hundreds of indexed animal studies, consistently favorable for treated groups across tendon, gut, and nervous-system injury models but the human evidence is thin: three small pilot studies, none controlled

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Healthcare providers may recommend weekly or bi-weekly administration schedules, with most patients experiencing initial results within 30 days of starting treatment

Higher doses (5mg twice weekly) used for severe injuries or accelerated healing timelines