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Moreover, synbiotics have been reported to improve gut integrity via SCFA production, by which inhibiting the TLR4LPS complex-triggered proinflammatory cascade, hampering proinflammatory cytokine signaling pathways, such as nuclear factor kappa B (NF-B), thereby decreasing insulin resistance (34)
This is why the American Society of Clinical Endocrinology suggests that patients stop taking these drugs even before starting a ketogenic diet [184]
