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VD obtained by sunlight exposure or through diet is converted to the main circulating form of VD, 25(OH)D, by 25 hydroxylase
treatment of blood cells with lead resulted in ROS-independent eryptosis without any increase in ROS, but with an increase in Ca 2+ level and caspase-3 activity
These enzymes bind toxins to glutathione molecules, making them water-soluble for easy elimination through bile or urine
