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It is class-wide counter-regulation: stopping removes the signal that was holding down a set-point the body still defends. The felt marker of the rebound is the return of food noise, which patients in the exit interviews reported as the first sign the loss was reversing. Metabolic loss tracks weight regain

According to SUCRA values, the top two ranked administration routes were the oral route (78.3) followed by the IM route (49.6) (Table 3(B))

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